For example, in specific breast cancer (MDA‐MB‐468, SK‐BR‐3, and 4T1) and melanoma (A375, A2058, and RPMI‐7951) cell lines, apigenin has shown efficacy in negating the upregulation of PD‐L1, an effect induced by IFN‐γ. Here, CD274 is linked to breast cancer.