Impressively, EGCG was able to induce apoptosis in cancer cells without manifesting notable toxicity to healthy cells.146 Recently, Dong and colleagues reported the nuanced relationship between EGCG and the WNT/β-catenin signaling pathway by demonstrating that overexpression of β-catenin could either augment or reduce the anticancer effects of EGCG.147 In addition, another study found that EGCG was involved in reducing the mRNA expression and transcriptional activity of β-catenin in wild-type P53-expressing KB cells. The gene discussed is TP53; the disease is cancer.