Functional experiments showed that FGF5-overexpressing NFs-derived CM slightly counteracted the effects of DDP on cell viability (Fig. S2C), MDA (Fig. S2D), Fe2+ (Fig. S2E), GSH (Fig. S2F) levels and lipid peroxidation (Fig. S1G) in NPC cells, which were not significantly in most cases. The gene discussed is FGF5; the disease is nasopharyngeal carcinoma.