Additionally, in active EoE the proportions of PLAC8+ macrophages, ALOX15+ macrophages, PRDM16+ DCs, and plasmacytoid DCs (pDCs) increased, while the proportions of FOLR2+ macrophages and apical cells decreased (Fig. 2a), highlighting additional findings in EoE. The gene discussed is PRDM16; the disease is eosinophilic esophagitis.