Previously unreported associations with the highest magnitude of significance included higher SMI with decreased cardiac dysrhythmias (OR [95% CI], 0.59 [0.55–0.64]; P < 0.0001), decreased epilepsy (OR, 0.59 [0.50–0.70]; P < 0.0001), and increased elevated prostate-specific antigen (OR, 1.84 [1.47–2.31]; P < 0.0001), and higher SMD with decreased decubitus ulcers (OR, 0.36 [0.31–0.42]; P < 0.0001), sleep disorders (OR, 0.39 [0.32–0.47]; P < 0.0001), and osteomyelitis (OR, 0.43 [0.36–0.52]; P < 0.0001). The gene discussed is KLK3; the disease is cardiac arrhythmia.