NYX and myopia: For example, the knockout of Nyx (nob mice) and Gpr179, both associated with CSNB1 and high myopia in humans, resulted in a larger myopic shift with FDM or LIM, coupled with lower retinal levels of dopamine and its primary metabolite, 3,4-dihydroxyphenylacetic acid (DOPAC) (Pardue et al. 2008, Wilmet et al. 2022).