For DFI, the data indicated that the high RRM2 expression was associated with the poor prognosis for cancers that included BRCA (P = 0.036), KIRP (P<0.001), LIHC (P = 0.021), LUAD (P<0.001), PAAD (P = 0.012), PRAD (P = 0.020), SARC (P = 0.002), and THCA (P<0.001). The gene discussed is RRM2; the disease is cancer.