RRM2 and cancer: For DFI (Fig 3K–3O and S2P-S2R Fig in S1 File), high RRM2 expression was linked to poor prognosis for cancers of KIRP (P = 0.007), LIHC (P = 0.038), LUAD (P = 0.005), PAAD (P = 0.022), SARC (P<0.001), TGCT (P = 0.043) and THCA (P = 0.001).