For PFI analysis data (Fig 3P–3T and S2A, S2B Fig in S1 File), high RRM2 expression was correlated with poor prognosis for ACC (P = 0.002), KICH (P = 0.007), KIRC (P = 0.025), KIRP (P<0.001), LGG (P = 0.001), LIHC (P = 0.003), LUAD (P = 0.003), MESO (P<0.001), PAAD (P = 0.002), PRAD (P<0.001), SARC (P = 0.001), THCA (P = 0.011), and UVM (P<0.001). Here, RRM2 is linked to adrenal cortex carcinoma.