TARDBP and amyotrophic lateral sclerosis: Further evaluation in additional FTLD-TDP and ALS patient samples revealed that our three mAbs can detect different morphologic subtypes of TDP-43 pathology including neuronal cytoplasmic inclusions (NCI), neuronal intranuclear inclusions (NCII), dystrophic neurites (DN), and diffuse granular neuronal cytoplasmic inclusions (dNCI); staining was absent in normal controls (Figs 5A‒5C and S3B).