Similarly, median (IQR) MPS2+ values were significantly higher in men with PCa of GG 2 or greater (0.54 [0.27-0.79]) relative to those with negative biopsies (0.08 [0.03-0.21]; P < .001) or those with cancer of GG 1 (0.25 [0.09-0.48]; P < .001). Here, IDS is linked to cancer.