Performance of Prostate-Specific Antigen (PSA) Alone, Prostate Cancer Prevention Trial Risk Calculator, Prostate Health Index (PHI), Derived Multiplex 2-Gene and 3-Gene Models, MyProstateScore (MPS), MPS2, and MPS2 Plus Prostate Volume (MPS2+) in the Validation Cohort. The gene discussed is KLK3; the disease is prostate cancer.