E2F6 and Nephroblastoma: Okutsu reported the aberrant expression of IGF2-AS in Wilms’ tumor and suggested the potential of IGF2-AS as one of the candidate Wilms’ tumor genes (Okutsu et al. 2000), while research about SLC9A3-AS1 reported the carcinogenic effect on NPC cells exerted by SLC9A3-AS1 through adjusting the miR-486-5p/E2F6 axis (Li et al. 2021).