The relationship between these eight lncRNAs and corresponding NRGs is shown in Fig. 4C. The comparison in the expression of these eight lncRNAs expression suggested that the expressions of LINC02454, SERTAD4-AS1, POLH-AS1 and HEATR6-DT were notably higher, whereas IRF1-AS1, SNHG1, IGF2-AS and SLC9A3-AS1 were more lowly expressed in tumor samples in comparison with normal soft tissue samples (p < 0.001; Fig. 4D). The gene discussed is IRF1; the disease is neoplasm.