NEB and nemaline myopathy: It has also been implicated in the regulation of thin filament length (TFL), as reduced levels of nebulin protein have been associated with shortened TFL in patients with NEB-related nemaline myopathy, as well as in nebulin-deficient mouse models, zebrafish, and chick skeletal myocytes [3, 36, 43, 61, 63, 64, 83, 102, 103].