We studied glucose disposal of LBWIs under steady-state hyperglycemia; the effect of exogenous insulin on glucose disposal in LBWIs, renal functions of LBWI with hyperglycemia, sympatho-adrenal response to hypoglycemia, hypoglycemia and congenital growth hormone deficiency, cord blood insulin levels, morbidities in infants of diabetic mothers, studies on hyperinsulinemia/nesidioblastosis, neonatal islet cell adenoma and gluconeogenesis in experimental intrauterine growth retardation in rats [20–29]. The gene discussed is INS; the disease is Hyperglycemia.