APOE and Alzheimer disease: AD patients versus cognitively healthy centenarians, excluding the two APOE SNPs: OR = 1.97, 95% CI = [1.74–2.23], P = 2.75 × 10−26; including APOE SNPs, OR = 5.07, 95% CI = [4.25–6.06], P = 1.54 × 10−71).