M1a, lymph node metastasis; M1b, bone metastasis; M1c, visceral metastasis (with or without bone metastasis); Mo, no metastasis; PSA, Prostate‐Specific Antigen; Range, minimum – maximum; SD, Standard Deviation; WHO PS, World Health Organization Performance Score. This evidence concerns the gene KLK3 and metastatic malignant neoplasm in the lymph nodes.