To further evaluate the relevance of VISTA, CTLA4, PD1and PDL1 expressions and TILs markers in HGSOC at the mRNA level, we assessed the correlation between the Vsir gene (encoding VISTA), CTLA4(encoding CTLA4), CD274(encoding PDL1), PDCD1 (encoding PD1), CD8A (encoding CD8), CD4 (encoding CD4) and FOXP3 (encoding FOXP3) according to the mRNA expression of 429 ovarian cancer patients downloaded from the TCGA database. The gene discussed is CD274; the disease is ovarian carcinoma.