MAPT and Alzheimer disease: HEK293T cell lines stably expressing tau-K18 P301S-eYFP were incubated with AD brain tissues and this model was used for FDA-approved small molecule drugs (~1700 compounds) and the ChemBridge CNS-set, a library of approximately 60,000 compounds, and the drugs identified are confidential (Seidler et al., 2022).