As well as the histologically defined RCCs (clear cell, papillary, oncocytic and chromophobe, collecting duct and histological variants), there are now 11 categories of molecularly defined renal cancers, for example, TFE3‐rearranged RCC, TFEB‐altered RCC, ELOC (formerly TCEB1)‐mutated RCC, fumarate hydratase‐deficient RCC, succinate dehydrogenase‐deficient RCC, ALK‐rearranged RCC and three categories of SWI/SNF‐related matric associated actin‐dependent regulator of chromatic subfamily B member 1 (SMARCB1) (INI1)‐deficient RCC. This evidence concerns the gene ELOC and renal carcinoma.