HGF and non-small cell lung carcinoma: In H1299, PC9, H1975, and PC9/ER human non-small-cell lung cancer (NSCLC) cell lines, praeruptorin A and pteryxin restricted the HGF-induced phosphorylation of MET in PC9/ER and H1975 cells, increased PARP cleavage in H1975 cells and the proportion of annexin V-positive cells, and overall induced apoptosis and reduced cell viability.