GRK4 and hypertensive disorder: Of the four GRK4 variants reported by Jones and colleagues [12], the GRK4 rs2960306 (c.194G>T, p.Arg65Leu), rs1024323 (c.425C>T, p.Ala142Val), and rs1801058 (c.1457T>C, p.Val486Ala) were previously reported to be associated with altered activity of the protein and hypertension.