Systemic FH levels were significantly lower in the early/intermediate AMD group (186.47 (72.11-931.78) ng/mL) compared to the advanced AMD (380.27 (5.39–2680) ng/mL) and the healthy control (415.23 (106.13-1962.21) ng/mL) groups (p=0.039) (Figure 1A). The gene discussed is FH; the disease is age-related macular degeneration.