A variety of autoimmune disorders are found with impaired Tregs, ranging from monogenic Tregopathies caused by mutations in Treg regulators like FOXP3, CTLA4, WASP, CD25, STAT5, and BACH2,22,23,24,25,26,27,28,29,30,31 to common diseases like type 1 diabetes, multiple sclerosis, rheumatoid arthritis and polyendocrine syndromes.32 This evidence concerns the gene FOXP3 and Autoimmunity.