CP and amyotrophic lateral sclerosis: Thus, future studies should be conducted to further examine whether CP enlargement can be detected in the earlier stages of ALS patients, for example, in ALS patients at King’s stage 1 or even in presymptomatic-stage patients with ALS, and the diagnostic performance of the CP volume in distinguishing between ALS and ALS-mimic diseases [1, 5, 34, 38].