NFKB1 and COVID-19: Some studies found EGCG can downregulate the expression of inflammatory mediators and signal transduction pathways by acting on signal transducers and activators of transcription (STAT) 1/3 and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) transcription factors [12], which could be considered as a potential nature immune homeostasis agent to counteract hyper-inflammation existing in COVID-19.