PYGB and Cirrhosis: Of the 36 cirrhosis variants, we identified protein-altering variants in LD (r2 > 0.8) with the lead variant at 16 loci (Supplementary Table 16), including 3 splice variants in HSD17B13 (rs72613567, c.812+2dupT), MAMSTR (rs11666792, c.219+3G>A) and PYGB (rs2261790, c.1518+6T>C).