A study suggested that adipose-derived mesenchymal stem cells/mesenchymal stromal cells exosomes (ADMSCs-Exos) may have the potential to reduce the concentrations of interferon (IFN)-γ and interleukin-17 (IL-17), while simultaneously augmenting the ratio of regulatory T cells (Treg) in spleen, as well as transforming growth factor beta (TGF-β), IL-4 and IL-10 in mice with T1DM. This evidence concerns the gene IL10 and type 1 diabetes mellitus.