Consistent with these findings, recent research further validated that MSCs-Exos possess the capability to attenuate the Th1 and Th17 cell differentiation, impede the activation of T cells, and enhance the production of IL-10, resulting in the repression of islet inflammation, a substantial increase of plasma insulin, and delaying the onset of T1DM effectively [7]. This evidence concerns the gene IL10 and type 1 diabetes mellitus.