In another investigation, elevated miRNA‐16‐5p in human USCs-Exos have the ability to inhibit the expression of inflammatory cytokines TNF‐α and chemokines CCL2 (also known as MCP-1) in the nephrocytes of rats with diabetes, resulting the downregulation of VEGFA expression, prevention of podocytes apoptosis, eventually with accompanying promotion of podocyte proliferation [59]. The gene discussed is VEGFA; the disease is diabetes mellitus.