In summary, METTL3, IGF2BP3, METTL14, and YTHDF2 enhance the expression in RCC of lncRNA NEAT1, lncRNA DMDRMR, lncRNA NEAT1_1, lncRNA LSG1, and circPOLR2A, respectively, by enhancing their stability through m6A modifications. Here, YTHDF2 is linked to renal cell carcinoma.