CCNL1 and posterior cortical atrophy: For example, Wen et al. [65] found that the lncRNA NEAT1 can bind to CYCLINL1 through the m6A site, increasing the activity of the CYCLINL1/CDK19 complex, then binding to the RUNX2 promoter to promote the transcription of RUNX2, eventually leading to PCa malignant progression and bone metastasis (Fig. 2E).