Followed by LASSO regression analysis and the Venn diagram, eight co-expression genes (SYT4, ENPP6, VMP1, LY6E, SHISA6, TMEM158, IL11, and KLK8) were discovered that identified some hub genes could be useful in predicting prognosis and management in GC (.Wu et al. 2023). The gene discussed is LY6E; the disease is gastric cancer.