When unchallenged, U2932 and SuDHL5 cells with various KLHL6 manipulations grew at a similar rate, however, silencing of KLHL6-sensitized and WT overexpression desensitized lymphoma cells for activation-induced cell death (AICD; Fig. 5M; Supplementary Fig. S7B and S7C). The gene discussed is KLHL6; the disease is lymphoma.