TNF and mastitis: Kaempferol suppressed phosphorylation of the NF-κB p65 subunit and the degradation of its inhibitor, IκBα, in the NF-κB signal pathway for the treatment of mastitis; this was accompanied by decreased myeloperoxidase (MPO) production and ANGPTL2 expression, as well as a reduction in TNF-α and IL-6 [52].