Grade 3–4 neutropenia occurred earlier in the G-CSF group with a median onset of day 0 (IQR -4.5–2.0) compared to day 5 (IQR 0.25–8.5) in the non-G-CSF group (P = 0.014) (Supplementary Table 2). The gene discussed is CSF3; the disease is neutropenia.