1. Closest similarities to humans. The formation of complex atherosclerotic lesions in coronary arteries. which demonstrates intimal thickening and increased density of vasa vasorum in the tunica media, features also observed in humans.2. Humanoid lipoprotein metabolism with a predominance of non-HDL lipoproteins, human-like HDL subclasses, and expression of CETP. 3. Upon feeding a high-fat diet, males develop more atherosclerosis than female animals, as is also the case in humans. Here, CETP is linked to atherosclerosis.