IL13 and allergic asthma: The release of alarmins or lipid mediators such as PGD2 and cysteinyl leukotrienes (CysLTs), stimulates ILC2s to produce TH2 cytokines, such as IL-5 and IL-13, leading to increased recruitment of eosinophils in mucosal sites and exacerbating the inflammatory process (59, 60), thus contributing to the development of allergic asthma.