MG-associated thymomas (MG+ thymomas) have been reported to show a thymopoiesis skewed towards CD4+ T cells characterized by an increased intratumor frequency of naïve CD3+CD4+CD45RA+ T cells compared with thymomas not associated to MG (MG- thymomas) (76, 77). Here, CD4 is linked to myasthenia gravis.