In the context of colon cancer, the proteins cysteine aspartic acid protease-3 (caspase 3), B-cell lymphoma 2 (Bcl-2), and B-cell lymphoma-extra large (Bcl-xL) are of particular interest due to their roles in apoptosis (programmed cell death) and their potential implications in cancer progression, including colon cancer. Here, CASP3 is linked to malignant colon neoplasm.