SERPING1 and hereditary angioedema: Intravenouslyadministered recombinant human C1-INH as well as plasma-derived C1-INH(pdC1-INH) have delivered safe and efficacious treatments of HAE attacks.HAE facilitates spontaneous and uncontrolled activation of the KKS.7 Patients have the potential to exhibit symptoms,such as subcutaneous and laryngeal swelling, and can also be accompaniedby severe abdominal pain and obstruction of major organs.8