Down‐regulation of OVOL2 has been found in many kinds of cancers.[16, 17, 18] We previously found that OVOL2 loss is associated with malignant progression in colorectal cancer.[19] OVOL2 suppresses the TGFβ1‐induced EMT process in breast cancer.[20] However, the role of OVOL2 in regulating fatty acid oxidation, particularly in TNBC, remains largely unknown. This evidence concerns the gene OVOL2 and breast cancer.