INS and polycystic ovary syndrome: Approximately 20 to 30% of PCOS patients are demonstrated to have excessed adrenal androgen secretion, primarily indicated by elevated levels of DHEAS [16].Individuals with hyperandrogenism who have elevated DHEAS levels tend to exhibit a leaner physique, lower insulin levels, and a more favorable metabolic profile, indicating that elevated DHEAS levels could potentially confer a protective effect against metabolic syndrome [17].