LMNA and breast cancer: Its expression pattern in breast cancer is, such that, PSCA protein in IMPC and IDC-NST acts as up-regulation and has the highest expression in these two types of breast cancer, while in ILC it acts as down-regulation and has the lowest expression, so targeted drug therapy for patients with overexpression of PSCA in IMPC may reduce the rate of cancer recurrence in these patients [70].