On the contrary, in a study exploring the cytokine profile (including IL-2, IL-10, IL-4, IL-6, IFN-γ, TNF-α, and IL-17) in patients experiencing their first episode of psychosis, no correlations were found between cytokine levels and the total PANSS score or the scores of the positive or negative subscales41. This evidence concerns the gene IL10 and psychotic disorder.