Although gastrointestinal and liver toxicities and cutaneous reactions were commonly seen with the inhibition of PI3Kδ,18,47 alanine aminotransferase (18.3% vs. 23–47%) and aspartate aminotransferase increased (14.6% vs. 28%-35%) were presented here at a lower incidence compared with idelalisib and copanlisib12,13; and no colitis was reported. Here, GPT is linked to colitis.