CXCL10 and neoplasm: In contrast, high UMIS metastases had lower tumor cell expression of CTNNB1, increased APC expression of T cell chemoattractant ligands (CXCL10 and CXCL9), greater tumor reactive TIL recruitment, and markedly elevated MHC expression on multiple cell populations within the tumor microenvironment, suggesting prominent interferon signaling.