In addition, several data from both humans and animal models consistently demonstrated the contribution of GALNT2 to several highly prevalent metabolic abnormalities related to insulin resistance, namely atherogenic dyslipidemia [6, 15–23], type 2 diabetes [24, 25], obesity [6, 17, 26] and polycystic ovary syndrome [27]. This evidence concerns the gene GALNT2 and type 2 diabetes mellitus.