Loss-of-function mutations in the FMR1 gene leading to fragile X syndrome (FXS) are the most frequent monogenetic cause (6–8%) of ASD in humans (Muhle et al., 2004; Fyke and Velinov, 2021), with a general prevalence of ASD at ∼2% of children (Baio et al., 2018). This evidence concerns the gene FMR1 and fragile X syndrome.