In the auditory cortex (AC) of FXS patients and FMR1 KO mice, electroencephalogram studies revealed increased amplitudes in event-related potentials and reduced habituation to repeated sounds, indicating a higher noise level in AC activity (Castrén et al., 2003; Ethridge et al., 2016; Lovelace et al., 2018; Wen et al., 2019). Here, FMR1 is linked to fragile X syndrome.