It was found that SCD was significantly negatively correlated with the degree of infiltration of Macrophages.M0 and Macrophages.M2, positively correlated with the degree of infiltration of Macrophages.M1, and significantly negatively correlated with the characteristic genes IRF4 and PTGS2 of Macrophages.M1. Here, PTGS2 is linked to Schnyder corneal dystrophy.