Researchers confirmed that citric acid can enhance the acetylation of the transcription factor RELA 310 of CD47 (anti macrophage phagocytic cell membrane protein) in brain glioma and promote NF- κ The activity of B increases the transcription level of CD47, but after inhibiting the acetylation of RELA K310, the above promotion is blocked. This evidence concerns the gene CD47 and brain glioma.