Of the two interactions surrounding HLD-DRB1 detected in males, one involves ZNF771—a gene that has been associated with male MS in transcriptomic meta analysis [47], while the other involves SLC1A6—a gene involved in regulation of the neurotransmitter glutamate [53], which is present in excess levels in MS patients [48]. The gene discussed is HLA-DRB1; the disease is myeloid sarcoma.