Note that symptoms such as acneiform rash, xerosis, eczema, paronychia, changes in the nails, arthralgia, or stiffness of limb joints, which are common side effects of EGFR inhibitors or aromatase inhibitors [59,60], might be extracted as closely related expressions to those of HFS signals. This evidence concerns the gene CYP19A1 and Eczematoid dermatitis.