Among the top upregulated genes was EEF1A1. Acetylated EEF1A1 negatively regulates remyelination in the peripheral nervous system and CNS, whereas deacetylated EEF1A1 can promote remyelination [65], therefore, upregulation of EEF1A1 could disrupt the remyelination process in RRMS patients. The gene discussed is EEF1A1; the disease is relapsing-remitting multiple sclerosis.