Dodge et al. also revealed the elevation levels of globotriaosylceramide, ceramide, lactosylceramide, glucosylceramide, galactocerebroside, and the gangliosides GM3 and GM1, as well as the hexosaminidase (HEX) activity in the spinal cords of ALS patients [13]. This evidence concerns the gene HHEX and amyotrophic lateral sclerosis.