Based on the results of the ROC curve analysis (Fig. 6), we found that the predictive effect of the combined group of FGF23 and α-klotho (area under the curve [AUC]: 0.7697) was slightly higher than that of FGF23 (AUC: 0.7558) for T2DM, and the AUC of α-klotho was the lowest (AUC: 0.5852). Here, KL is linked to type 2 diabetes mellitus.