Real-time polymerase chain reaction (RT-PCR) and immunofluorescence staining revealed that the expression of TGF-β1, VEGF-A, VEGF-B, vWF, and Serca2a genes, as well as myocardium-associated proteins, such as CD31, Cx43, α-SMA, and Ki67, were significantly upregulated in damaged cardiomyocytes, which had a significant therapeutic effect on myocardial infarction (MI). The gene discussed is ACTA1; the disease is myocardial infarction.