Homozygous pathogenic PLA2G6 variants are the causes of Infantile neuroaxonal dystrophy 1 (OMIM #256600), Neurodegeneration with brain iron accumulation 2B (OMIM #610217), and Parkinson disease 14 (OMIM #612953). This evidence concerns the gene PLA2G6 and Adult-onset dystonia-parkinsonism.